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Kengo Watanabe Selected Research

Chronic Disease (Chronic Diseases)

11/2018Discovery of DS42450411 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4-aminopyrimidine derivatives.
12/2017Discovery of DS28120313 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4,6-disubstituted indazole derivatives.
1/2017Discovery of DS79182026: A potent orally active hepcidin production inhibitor.
1/2017Synthesis and SAR studies of 3,6-disubstituted indazole derivatives as potent hepcidin production inhibitors.

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Kengo Watanabe Research Topics

Disease

4Anemia
11/2018 - 01/2017
4Chronic Disease (Chronic Diseases)
11/2018 - 01/2017
3Neoplasms (Cancer)
08/2019 - 11/2007
1Neoplasm Metastasis (Metastasis)
08/2019
1Lung Neoplasms (Lung Cancer)
01/2019
1Inflammation (Inflammations)
11/2018
1AIDS-Related Complex (ARC)
01/2018
1Drug-Related Side Effects and Adverse Reactions
10/2010
1Body Weight (Weight, Body)
11/2007

Drug/Important Bio-Agent (IBA)

4HepcidinsIBA
11/2018 - 01/2017
1Carrier Proteins (Binding Protein)IBA
08/2019
1CrizotinibIBA
01/2019
1Phosphotransferases (Kinase)IBA
01/2019
1lorlatinibIBA
01/2019
1entrectinibIBA
01/2019
1Leucine (L-Leucine)FDA Link
01/2018
1IronIBA
12/2017
1Carboxylic AcidsIBA
10/2010
1GlucuronidesIBA
10/2010
1ethylene dichloride (1,2-dichloroethane)IBA
11/2007
1Methylene Chloride (Dichloromethane)IBA
11/2007
1DNA (Deoxyribonucleic Acid)IBA
11/2007
1methylene bromide (dibromomethane)IBA
11/2007

Therapy/Procedure

1Drug Therapy (Chemotherapy)
08/2019
1Therapeutics
08/2019